14-3-3σ and Its Modulators in Cancer

14-3-3σ and Its Modulators in Cancer

14-3-3σ is an acidic homodimer protein with more than one hundred different protein partners associated with oncogenic signaling and cell cycle regulation. This review aims to highlight the crucial role of 14-3-3σ in controlling tumor growth and apoptosis and provide a detailed discussion on the str...

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Bibliographic Details
Main Authors:	Ghazi Aljabal, Beow Keat Yap
Format:	Article
Language:	English
Published:	MDPI AG 2020-12-01
Series:	Pharmaceuticals
Subjects:	protein-protein interaction (PPI) 14-3-3σ dimer stabilizer inhibitor cancer
Online Access:	https://www.mdpi.com/1424-8247/13/12/441

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