<i>N</i>-Heterocyclic Carbene-Platinum Complexes Featuring an Anthracenyl Moiety: Anti-Cancer Activity and DNA Interaction

<i>N</i>-Heterocyclic Carbene-Platinum Complexes Featuring an Anthracenyl Moiety: Anti-Cancer Activity and DNA Interaction

A platinum (II) complex stabilized by a pyridine and an N-heterocyclic carbene ligand featuring an anthracenyl moiety was prepared. The compound was fully characterized and its molecular structure was determined by single-crystal X-ray diffraction. The compound demonstrated high in vitro antiprolife...

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Bibliographic Details
Main Authors: Sébastien Harlepp, Edith Chardon, Mathilde Bouché, Georges Dahm, Mounir Maaloum, Stéphane Bellemin-Laponnaz
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:International Journal of Molecular Sciences
Subjects:
antitumoral activity
platinum
N-heterocyclic carbene
two-state interaction
AFM and optical tweezers microscopy
Online Access:https://www.mdpi.com/1422-0067/20/17/4198

Internet

https://www.mdpi.com/1422-0067/20/17/4198

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