Expression of antizyme inhibitor 2 in mast cells and role of polyamines as selective regulators of serotonin secretion.

BACKGROUND:Upon IgE-mediated activation, mast cells (MC) exocytose their cytoplasmic secretory granules and release a variety of bioactive substances that trigger inflammatory responses. Polyamines mediate numerous cellular and physiological functions. We report here that MCs express antizyme inhibi...

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Bibliographic Details
Main Authors: Kristiina Kanerva, Jani Lappalainen, Laura T Mäkitie, Susanna Virolainen, Petri T Kovanen, Leif C Andersson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-08-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2730566?pdf=render