Structural and mechanistic basis of proton-coupled metal ion transport in the SLC11/NRAMP family

Cellular uptake of transition metal ions is mediated by members of the SLC11/NRAMP family. Here the authors determine the structural and functional properties of EcoDMT, a bacterial SLC11 transporter, gathering molecular insight into its transport mechanism and proton coupling process.

Bibliographic Details
Main Authors: Ines A. Ehrnstorfer, Cristina Manatschal, Fabian M. Arnold, Juerg Laederach, Raimund Dutzler
Format: Article
Language:English
Published: Nature Publishing Group 2017-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms14033