Mechanism for adhesion G protein-coupled receptor GPR56-mediated RhoA activation induced by collagen III stimulation.

Mechanism for adhesion G protein-coupled receptor GPR56-mediated RhoA activation induced by collagen III stimulation.

GPR56 is a member of the adhesion G protein-coupled receptor (GPCR) family. Despite the importance of GPR56 in brain development, where mutations cause a devastating human brain malformation called bilateral frontoparietal polymicrogyria (BFPP), the signaling mechanism(s) remain largely unknown. Lik...

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Bibliographic Details
Main Authors: Rong Luo, Sung-Jin Jeong, Annie Yang, Miaoyun Wen, David E Saslowsky, Wayne I Lencer, Demet Araç, Xianhua Piao
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4065004?pdf=render

Internet

http://europepmc.org/articles/PMC4065004?pdf=render

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