NFκB- and MAP-Kinase Signaling Contribute to the Activation of Murine Myeloid Dendritic Cells by a Flagellin A: Allergen Fusion Protein

NFκB- and MAP-Kinase Signaling Contribute to the Activation of Murine Myeloid Dendritic Cells by a Flagellin A: Allergen Fusion Protein

Fusion proteins incorporating the TLR5-ligand flagellin are currently undergoing clinical trials as vaccine candidates for many diseases. We recently reported a flagellin:allergen fusion protein containing the TLR5-ligand flagellin A (FlaA) from <i>Listeria monocytogenes</i> and the majo...

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Bibliographic Details
Main Authors: Tobias Moeller, Sonja Wolfheimer, Alexandra Goretzki, Stephan Scheurer, Stefan Schülke
Format: Article
Language:English
Published: MDPI AG 2019-04-01
Series:Cells
Subjects:
flagellin
TLR5
Bet v 1
birch allergy
vaccine
fusion protein
metabolism
MAPK
NFκB
signalling
Online Access:https://www.mdpi.com/2073-4409/8/4/355

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