5-Azacytidine Induces Anoikis, Inhibits Mammosphere Formation and Reduces Metalloproteinase 9 Activity in MCF-7 Human Breast Cancer Cells

5-Azacytidine Induces Anoikis, Inhibits Mammosphere Formation and Reduces Metalloproteinase 9 Activity in MCF-7 Human Breast Cancer Cells

Cancer stem cells are a subset of cancer cells that initiate the growth of tumors. Low levels of cancer stem cells also exist in established cancer cell lines, and can be enriched in serum-free tumorsphere cultures. Since cancer stem cells have been reported to be resilient to common chemotherapeuti...

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Bibliographic Details
Main Authors: Hsueh-Wei Chang, Hui-Chun Wang, Chiau-Yi Chen, Ting-Wei Hung, Ming-Feng Hou, Shyng-Shiou F. Yuan, Chih-Jen Huang, Chao-Neng Tseng
Format: Article
Language:English
Published: MDPI AG 2014-03-01
Series:Molecules
Subjects:
cancer stem cell
breast cancer
anoikis
Online Access:http://www.mdpi.com/1420-3049/19/3/3149

Internet

http://www.mdpi.com/1420-3049/19/3/3149

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