Liver X Receptor Agonist TO901317 Prevents Diacylglycerols Accumulation in the Heart of Streptozotocin-Diabetic Rats

Liver X Receptor Agonist TO901317 Prevents Diacylglycerols Accumulation in the Heart of Streptozotocin-Diabetic Rats

Background/Aims: Liver X receptors (LXRα and LXRβ) are ligand-activated transcription factors that regulate expression of genes involved in lipid and cholesterol metabolism. LXR expression has been identified in the heart, and enhanced LXR activity in the streptozotocin (STZ) diabetic myocardium was...

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Bibliographic Details
Main Authors: Dorota Harasiuk, Marcin Baranowski, Piotr Zabielski, Adrian Chabowski, Jan Górski
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2016-06-01
Series:Cellular Physiology and Biochemistry
Subjects:
Myocardium
Fatty acids
DAG
Cardiac muscle
Nuclear receptors
Type 1 diabetes
Online Access:http://www.karger.com/Article/FullText/445629

Internet

http://www.karger.com/Article/FullText/445629

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