Permeability of membranes in the liquid ordered and liquid disordered phases

Permeability of membranes in the liquid ordered and liquid disordered phases

Increasing evidence supports the existence of ordered nanodomains (or rafts) in cholesterol rich cell membranes. Here authors present molecular dynamics simulations and EPR experiments to monitor permeation of oxygen and water through membranes in the liquid ordered and liquid disordered phases.

Bibliographic Details
Main Authors: An Ghysels, Andreas Krämer, Richard M. Venable, Walter E. Teague, Edward Lyman, Klaus Gawrisch, Richard W. Pastor
Format: Article
Language:English
Published: Nature Publishing Group 2019-12-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-13432-7
id doaj-e91db752ad0d4f168ae8b7aecf6084be
record_format Article
spelling doaj-e91db752ad0d4f168ae8b7aecf6084be2021-05-11T11:23:31ZengNature Publishing GroupNature Communications2041-17232019-12-0110111210.1038/s41467-019-13432-7Permeability of membranes in the liquid ordered and liquid disordered phasesAn Ghysels0Andreas Krämer1Richard M. Venable2Walter E. Teague3Edward Lyman4Klaus Gawrisch5Richard W. Pastor6Center for Molecular Modeling, Ghent UniversityLaboratory of Computational Biology, National Heart Lung Blood Institute, National Institutes of HealthLaboratory of Computational Biology, National Heart Lung Blood Institute, National Institutes of HealthLaboratory of Membrane Biochemistry and Biophysics, National Institute on Alcohol Abuse and Alcoholism, National Institutes of HealthDepartment of Physics and Astronomy and Department of Chemistry and Biochemistry, University of DelawareLaboratory of Membrane Biochemistry and Biophysics, National Institute on Alcohol Abuse and Alcoholism, National Institutes of HealthLaboratory of Computational Biology, National Heart Lung Blood Institute, National Institutes of HealthIncreasing evidence supports the existence of ordered nanodomains (or rafts) in cholesterol rich cell membranes. Here authors present molecular dynamics simulations and EPR experiments to monitor permeation of oxygen and water through membranes in the liquid ordered and liquid disordered phases.https://doi.org/10.1038/s41467-019-13432-7
collection DOAJ
language English
format Article
sources DOAJ
author An Ghysels
Andreas Krämer
Richard M. Venable
Walter E. Teague
Edward Lyman
Klaus Gawrisch
Richard W. Pastor
spellingShingle An Ghysels
Andreas Krämer
Richard M. Venable
Walter E. Teague
Edward Lyman
Klaus Gawrisch
Richard W. Pastor
Permeability of membranes in the liquid ordered and liquid disordered phases
Nature Communications
author_facet An Ghysels
Andreas Krämer
Richard M. Venable
Walter E. Teague
Edward Lyman
Klaus Gawrisch
Richard W. Pastor
author_sort An Ghysels
title Permeability of membranes in the liquid ordered and liquid disordered phases
title_short Permeability of membranes in the liquid ordered and liquid disordered phases
title_full Permeability of membranes in the liquid ordered and liquid disordered phases
title_fullStr Permeability of membranes in the liquid ordered and liquid disordered phases
title_full_unstemmed Permeability of membranes in the liquid ordered and liquid disordered phases
title_sort permeability of membranes in the liquid ordered and liquid disordered phases
publisher Nature Publishing Group
series Nature Communications
issn 2041-1723
publishDate 2019-12-01
description Increasing evidence supports the existence of ordered nanodomains (or rafts) in cholesterol rich cell membranes. Here authors present molecular dynamics simulations and EPR experiments to monitor permeation of oxygen and water through membranes in the liquid ordered and liquid disordered phases.
url https://doi.org/10.1038/s41467-019-13432-7
work_keys_str_mv AT anghysels permeabilityofmembranesintheliquidorderedandliquiddisorderedphases
AT andreaskramer permeabilityofmembranesintheliquidorderedandliquiddisorderedphases
AT richardmvenable permeabilityofmembranesintheliquidorderedandliquiddisorderedphases
AT waltereteague permeabilityofmembranesintheliquidorderedandliquiddisorderedphases
AT edwardlyman permeabilityofmembranesintheliquidorderedandliquiddisorderedphases
AT klausgawrisch permeabilityofmembranesintheliquidorderedandliquiddisorderedphases
AT richardwpastor permeabilityofmembranesintheliquidorderedandliquiddisorderedphases
_version_ 1721446587397308416

Similar Items