TANGO1 membrane helices create a lipid diffusion barrier at curved membranes

TANGO1 membrane helices create a lipid diffusion barrier at curved membranes

We have previously shown TANGO1 organises membranes at the interface of the endoplasmic reticulum (ER) and ERGIC/Golgi (Raote et al., 2018). TANGO1 corrals retrograde membranes at ER exit sites to create an export conduit. Here the retrograde membrane is, in itself, an anterograde carrier. This mode...

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Bibliographic Details
Main Authors: Ishier Raote, Andreas M Ernst, Felix Campelo, James E Rothman, Frederic Pincet, Vivek Malhotra
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-05-01
Series:eLife
Subjects:
membrane curvature
lipid
collagen
transmembrane
intramembrane
secretion
Online Access:https://elifesciences.org/articles/57822

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