Nonbacterial thrombotic endocarditis as an initial presentation of advanced cholangiocarcinoma in a young patient: A case report

• Main Authors: Bandar Al-Ghamdi, Fahmi A Alkaf, Menwar M Al-Anazi, Yahya Al Hebaishi, Normeen A Al Othimeen, Asirvatham Alwin Robert, Osman Ahmed, Abdullah Alkhushail
• Format: Article
• Language: English
• Published: SAGE Publishing 2020-08-01
• Series: SAGE Open Medical Case Reports
• Online Access: https://doi.org/10.1177/2050313X20945896

Nonbacterial thrombotic endocarditis, a form of noninfectious thrombotic endocarditis, is mainly characterized by deposition of sterile platelet thrombi on heart valves. Usually, it is observed in advanced malignancy. Herein, we report a case of a previously healthy male with recent unprovoked deep vein thrombosis presented with acute ischemic stroke. The echocardiogram revealed aortic and mitral valve masses. Eventually, he was discovered to have advanced cholangiocarcinoma. The present case, apart from being the youngest reported case, is among the few reported cases which manifest the association between cholangiocarcinoma and nonbacterial thrombotic endocarditis.