Non-viral Gene Delivery Methods for Bone and Joints

Viral carrier transport efficiency of gene delivery is high, depending on the type of vector. However, viral delivery poses significant safety concerns such as inefficient/unpredictable reprogramming outcomes, genomic integration, as well as unwarranted immune responses and toxicity. Thus, non-viral...

Full description

Bibliographic Details
Main Authors: Benjamin Gantenbein, Shirley Tang, Julien Guerrero, Natalia Higuita-Castro, Ana I. Salazar-Puerta, Andreas S. Croft, Amiq Gazdhar, Devina Purmessur
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2020.598466/full