Assessment of Linezolid Efficacy, Safety and Tolerability in the Treatment of Tuberculosis: A Retrospective Case Review

Assessment of Linezolid Efficacy, Safety and Tolerability in the Treatment of Tuberculosis: A Retrospective Case Review

Linezolid is a potentially effective drug for the treatment of patients with drug-resistant tuberculosis. Among 13 patients treated for tuberculosis with linezolid in the present study, nine had treatment success and four remain on treatment. Adverse effects occurred in 11 (85%) patients, of whom th...

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Main Authors: Alena Tse-Chang, Dennis Kunimoto, Evelina Der, Rabia Ahmed
Format: Article
Language:English
Published: Hindawi Limited 2013-01-01
Series:Canadian Journal of Infectious Diseases and Medical Microbiology
Online Access:http://dx.doi.org/10.1155/2013/535616
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spelling doaj-e8fe1904b2f34cb1b299299016b230b92021-07-02T09:28:09ZengHindawi LimitedCanadian Journal of Infectious Diseases and Medical Microbiology1712-95322013-01-01243e50e5210.1155/2013/535616Assessment of Linezolid Efficacy, Safety and Tolerability in the Treatment of Tuberculosis: A Retrospective Case ReviewAlena Tse-Chang0Dennis Kunimoto1Evelina Der2Rabia Ahmed3Department of Pediatrics, University of Alberta, Edmonton, Alberta, CanadaDepartment of Medicine, University of Alberta, Edmonton, Alberta, CanadaCentral TB Services, Alberta Health Services, Edmonton, Alberta, CanadaDepartment of Medicine, University of Alberta, Edmonton, Alberta, CanadaLinezolid is a potentially effective drug for the treatment of patients with drug-resistant tuberculosis. Among 13 patients treated for tuberculosis with linezolid in the present study, nine had treatment success and four remain on treatment. Adverse effects occurred in 11 (85%) patients, of whom three discontinued treatment because of adverse effects. The present study adds to the growing evidence supporting the efficacy of linezolid for tuberculosis, although treatment remains complicated by adverse effects.http://dx.doi.org/10.1155/2013/535616
collection DOAJ
language English
format Article
sources DOAJ
author Alena Tse-Chang
Dennis Kunimoto
Evelina Der
Rabia Ahmed
spellingShingle Alena Tse-Chang
Dennis Kunimoto
Evelina Der
Rabia Ahmed
Assessment of Linezolid Efficacy, Safety and Tolerability in the Treatment of Tuberculosis: A Retrospective Case Review
Canadian Journal of Infectious Diseases and Medical Microbiology
author_facet Alena Tse-Chang
Dennis Kunimoto
Evelina Der
Rabia Ahmed
author_sort Alena Tse-Chang
title Assessment of Linezolid Efficacy, Safety and Tolerability in the Treatment of Tuberculosis: A Retrospective Case Review
title_short Assessment of Linezolid Efficacy, Safety and Tolerability in the Treatment of Tuberculosis: A Retrospective Case Review
title_full Assessment of Linezolid Efficacy, Safety and Tolerability in the Treatment of Tuberculosis: A Retrospective Case Review
title_fullStr Assessment of Linezolid Efficacy, Safety and Tolerability in the Treatment of Tuberculosis: A Retrospective Case Review
title_full_unstemmed Assessment of Linezolid Efficacy, Safety and Tolerability in the Treatment of Tuberculosis: A Retrospective Case Review
title_sort assessment of linezolid efficacy, safety and tolerability in the treatment of tuberculosis: a retrospective case review
publisher Hindawi Limited
series Canadian Journal of Infectious Diseases and Medical Microbiology
issn 1712-9532
publishDate 2013-01-01
description Linezolid is a potentially effective drug for the treatment of patients with drug-resistant tuberculosis. Among 13 patients treated for tuberculosis with linezolid in the present study, nine had treatment success and four remain on treatment. Adverse effects occurred in 11 (85%) patients, of whom three discontinued treatment because of adverse effects. The present study adds to the growing evidence supporting the efficacy of linezolid for tuberculosis, although treatment remains complicated by adverse effects.
url http://dx.doi.org/10.1155/2013/535616
work_keys_str_mv AT alenatsechang assessmentoflinezolidefficacysafetyandtolerabilityinthetreatmentoftuberculosisaretrospectivecasereview
AT denniskunimoto assessmentoflinezolidefficacysafetyandtolerabilityinthetreatmentoftuberculosisaretrospectivecasereview
AT evelinader assessmentoflinezolidefficacysafetyandtolerabilityinthetreatmentoftuberculosisaretrospectivecasereview
AT rabiaahmed assessmentoflinezolidefficacysafetyandtolerabilityinthetreatmentoftuberculosisaretrospectivecasereview
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