SNP interaction detection with Random Forests in high-dimensional genetic data

<p>Abstract</p> <p>Background</p> <p>Identifying variants associated with complex human traits in high-dimensional data is a central goal of genome-wide association studies. However, complicated etiologies such as gene-gene interactions are ignored by the univariate ana...

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Bibliographic Details
Main Authors: Winham Stacey J, Colby Colin L, Freimuth Robert R, Wang Xin, de Andrade Mariza, Huebner Marianne, Biernacka Joanna M
Format: Article
Language:English
Published: BMC 2012-07-01
Series:BMC Bioinformatics
Online Access:http://www.biomedcentral.com/1471-2105/13/164