Gut Microbiota-Dependent Trimethylamine N-Oxide Associates With Inflammation in Common Variable Immunodeficiency

Gut Microbiota-Dependent Trimethylamine N-Oxide Associates With Inflammation in Common Variable Immunodeficiency

A substantial proportion of patients with common variable immunodeficiency (CVID) have inflammatory and autoimmune complications of unknown etiology. We have previously shown that systemic inflammation in CVID correlates with their gut microbial dysbiosis. The gut microbiota dependent metabolite tri...

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Bibliographic Details
Main Authors: Magnhild E. Macpherson, Johannes R. Hov, Thor Ueland, Tuva B. Dahl, Martin Kummen, Kari Otterdal, Kristian Holm, Rolf K. Berge, Tom E. Mollnes, Marius Trøseid, Bente Halvorsen, Pål Aukrust, Børre Fevang, Silje F. Jørgensen
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Immunology
Subjects:
TMAO
CVID
gut microbiota
immunodeficiency
inflammation
CutC
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.574500/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2020.574500/full

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