DNA aptamers against exon v10 of CD44 inhibit breast cancer cell migration.

DNA aptamers against exon v10 of CD44 inhibit breast cancer cell migration.

CD44 adhesion molecules are expressed in many breast cancer cells and have been demonstrated to play a key role in regulating malignant phenotypes such as growth, migration, and invasion. CD44 is an integral transmembrane protein encoded by a single 20-exon gene. The diversity of the biological func...

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Bibliographic Details
Main Authors: Joji Iida, Rebecca Clancy, Jesse Dorchak, Richard I Somiari, Stella Somiari, Mary Lou Cutler, Richard J Mural, Craig D Shriver
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3929491?pdf=render

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