FGF13 Is a Novel Regulator of NF-κB and Potentiates Pathological Cardiac Hypertrophy

Summary: FGF13 is an intracellular FGF factor. Its role in cardiomyopathies has been rarely investigated. We revealed that endogenous FGF13 is up-regulated in cardiac hypertrophy accompanied by increased nuclear localization. The upregulation of FGF13 plays a deteriorating role both in hypertrophic...

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Main Authors: Jia Sun, Chao Niu, Weijian Ye, Ning An, Gen Chen, Xiaozhong Huang, Jianan Wang, Xixi Chen, Yingjie Shen, Shuai Huang, Ying Wang, Xu Wang, Yang Wang, Litai Jin, Weitao Cong, Xiaokun Li
Format: Article
Language:English
Published: Elsevier 2020-10-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004220308191