The seed of Litchi chinensis fraction ameliorates hippocampal neuronal injury in an Aβ25-35-induced Alzheimer’s disease rat model via the AKT/GSK-3β pathway

The seed of Litchi chinensis fraction ameliorates hippocampal neuronal injury in an Aβ25-35-induced Alzheimer’s disease rat model via the AKT/GSK-3β pathway

Context The seed of Litchi chinensis Sonn., a famous traditional Chinese medicine, was recently reported to enhance cognitive function by inhibiting neuronal apoptosis in rats. Objective We determined whether the seed of Litchi chinensis fraction (SLF) can ameliorate hippocampal neuronal injury via...

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Bibliographic Details
Main Authors: Yueshan Sun, Anguo Wu, Xiu Li, Dalian Qin, Bingjin Jin, Jian Liu, Yong Tang, Jianming Wu, Chonglin Yu
Format: Article
Language:English
Published: Taylor & Francis Group 2020-01-01
Series:Pharmaceutical Biology
Subjects:
litchi chinensis seed fraction
neuroprotection
ad
botanical drug
cognitive function
beta-amyloid
tau
akt
gsk-3β
Online Access:http://dx.doi.org/10.1080/13880209.2019.1697298

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