CREB3 Transcription Factors: ER-Golgi Stress Transducers as Hubs for Cellular Homeostasis

CREB3 Transcription Factors: ER-Golgi Stress Transducers as Hubs for Cellular Homeostasis

CREB3 family of transcription factors are ER localized proteins that belong to the bZIP family. They are transported from the ER to the Golgi, cleaved by S1P and S2P proteases and the released N-terminal domains act as transcription factors. CREB3 family members regulate the expression of a large va...

Full description

Bibliographic Details
Main Authors: Luciana Sampieri, Pablo Di Giusto, Cecilia Alvarez
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-07-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
CREB3 transcription factors
ER stress response
Golgi stress response
secretory pathway
secretory capacity
cellular homeostasis
Online Access:https://www.frontiersin.org/article/10.3389/fcell.2019.00123/full

Similar Items

Similar Items