Improved HIV-positive infant survival is correlated with high levels of HIV-specific ADCC activity in multiple cohorts

Improved HIV-positive infant survival is correlated with high levels of HIV-specific ADCC activity in multiple cohorts

Summary: Defining immune responses that protect humans against diverse HIV strains has been elusive. Studying correlates of protection from mother-to-child transmission provides a benchmark for HIV vaccine protection because passively transferred HIV antibodies are present during infant exposure to...

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Bibliographic Details
Main Authors:	Zak A. Yaffe, Nicole E. Naiman, Jennifer Slyker, Bruce D. Wines, Barbra A. Richardson, P. Mark Hogarth, Rose Bosire, Carey Farquhar, Dorothy Mbori Ngacha, Ruth Nduati, Grace John-Stewart, Julie Overbaugh
Format:	Article
Language:	English
Published:	Elsevier 2021-04-01
Series:	Cell Reports Medicine
Subjects:	human immunodeficiency virus (HIV) antibody-dependent cellular cytotoxicity (ADCC) mother-to-child transmission (MTCT) passive antibody transfer maternal antibodies pediatric HIV
Online Access:	http://www.sciencedirect.com/science/article/pii/S2666379121000707

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