Endoplasmic reticulum stress participates in the pathophysiology of mercury-caused acute kidney injury

Endoplasmic reticulum stress participates in the pathophysiology of mercury-caused acute kidney injury

Acute exposure to mercury chloride (HgCl2) causes acute kidney injury (AKI). Some metals interfere with protein folding, leading to endoplasmic reticulum stress (ERS), and the activation of cell death mechanisms, but in the case of mercury, there is no knowledge about whether the ERS mediates tubula...

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Bibliographic Details
Main Authors: Plácido Rojas-Franco, Margarita Franco-Colín, Alejandra Paola Torres-Manzo, Vanessa Blas-Valdivia, María del Rocio Thompson-Bonilla, Sinan Kandir, Edgar Cano-Europa
Format: Article
Language:English
Published: Taylor & Francis Group 2019-01-01
Series:Renal Failure
Subjects:
mercury nephrotoxicity
acute kidney injury
mercury chloride
endoplasmic reticulum stress
unfolded protein response
Online Access:http://dx.doi.org/10.1080/0886022X.2019.1686019

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