Broad epigenetic signature of maternal care in the brain of adult rats.

Broad epigenetic signature of maternal care in the brain of adult rats.

Maternal care is associated with long-term effects on behavior and epigenetic programming of the NR3C1 (GLUCOCORTICOID RECEPTOR) gene in the hippocampus of both rats and humans. In the rat, these effects are reversed by cross-fostering, demonstrating that they are defined by epigenetic rather than g...

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Bibliographic Details
Main Authors: Patrick O McGowan, Matthew Suderman, Aya Sasaki, Tony C T Huang, Michael Hallett, Michael J Meaney, Moshe Szyf
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-02-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3046141?pdf=render

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