Colorectal carcinomas with microsatellite instability display a different pattern of target gene mutations according to large bowel site of origin

Colorectal carcinomas with microsatellite instability display a different pattern of target gene mutations according to large bowel site of origin

<p>Abstract</p> <p>Background</p> <p>Only a few studies have addressed the molecular pathways specifically involved in carcinogenesis of the distal colon and rectum. We aimed to identify potential differences among genetic alterations in distal colon and rectal carcinom...

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Main Authors: Santos Lúcio, Fragoso Maria, Sousa Olga, Afonso Luís, Costa Vera, Pinto Carla, Veiga Isabel, Lind Guro E, Danielsen Stine A, Ahlquist Terje, Pinheiro Manuela, Henrique Rui, Lopes Paula, Lopes Carlos, Lothe Ragnhild A, Teixeira Manuel R
Format: Article
Language:English
Published: BMC 2010-10-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/10/587

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