Mitochondrial RNA Expression and Single Nucleotide Variants in Association with Clinical Parameters in Primary Breast Cancers

Mitochondrial RNA Expression and Single Nucleotide Variants in Association with Clinical Parameters in Primary Breast Cancers

The human mitochondrial DNA (mtDNA) encodes 37 genes, including thirteen proteins essential for the respiratory chain, and RNAs functioning in the mitochondrial translation apparatus. The total number of mtDNA molecules per cell (mtDNA content) is variable between tissue types and also between tumor...

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Bibliographic Details
Main Authors: Marjolein J. A. Weerts, Marcel Smid, John A. Foekens, Stefan Sleijfer, John W. M. Martens
Format: Article
Language:English
Published: MDPI AG 2018-12-01
Series:Cancers
Subjects:
primary breast cancer
mitochondrial RNA variants
mitochondrial expression
clinicopathological markers
Online Access:https://www.mdpi.com/2072-6694/10/12/500

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