Joint analysis for genome-wide association studies in family-based designs.

In family-based data, association information can be partitioned into the between-family information and the within-family information. Based on this observation, Steen et al. (Nature Genetics. 2005, 683-691) proposed an interesting two-stage test for genome-wide association (GWA) studies under fami...

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Bibliographic Details
Main Authors: Qiuying Sha, Zhaogong Zhang, Shuanglin Zhang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3142116?pdf=render