Active zone proteins are transported via distinct mechanisms regulated by Par-1 kinase.
Disruption of synapses underlies a plethora of neurodevelopmental and neurodegenerative disease. Presynaptic specialization called the active zone plays a critical role in the communication with postsynaptic neuron. While the role of many proteins at the active zones in synaptic communication is rel...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2017-02-01
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Series: | PLoS Genetics |
Online Access: | http://europepmc.org/articles/PMC5340405?pdf=render |