Anti PD-1 protitelesa
Protein programirane celične smrti 1:PD-1 (Programmed cell death protein 1) je transmembranski protein, ki je izražen na celicah T, B, NK ter monocitih in dendritičnih celicah. Vezava med PD-1 in njegovimi ligandi zavira tumorsko celično apoptozo, spodbuja izčrpanost T-celic in preprečuje aktiven an...
Main Author: | Janja Ocvirk |
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Format: | Article |
Language: | Slovenian |
Published: |
Institute of Oncology Ljubljana
2017-12-01
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Series: | Onkologija |
Subjects: | |
Online Access: | https://revijaonkologija.si/Onkologija/article/view/52 |
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