Altered levels of mitochondrial DNA are associated with female age, aneuploidy, and provide an independent measure of embryonic implantation potential.

Altered levels of mitochondrial DNA are associated with female age, aneuploidy, and provide an independent measure of embryonic implantation potential.

Mitochondria play a vital role in embryo development. They are the principal site of energy production and have various other critical cellular functions. Despite the importance of this organelle, little is known about the extent of variation in mitochondrial DNA (mtDNA) between individual human emb...

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Bibliographic Details
Main Authors: Elpida Fragouli, Katharina Spath, Samer Alfarawati, Fiona Kaper, Andrew Craig, Claude-Edouard Michel, Felix Kokocinski, Jacques Cohen, Santiago Munne, Dagan Wells
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-06-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC4454688?pdf=render

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