WHAT DOES ABACTERIAL PROSTATITITS HIDE?

• Main Authors: А. А. Breusoff, Е. V. Кulchavenya, А. G. Cherednichenko, S. V. Stovbun
• Format: Article
• Language: Russian
• Published: State Budget Educational Institute of Higher Professional Education, Rostov State Medical University, Ministry Health of Russian Federation 2017-07-01
• Series: Vestnik Urologii
• Subjects: chronic abacterial prostatitis; chlamydia trachomatis; virus herpes; prostatitis; therapy
• Online Access: https://www.urovest.ru/jour/article/view/148

Introduction. It seems 90% of chronic prostatitis (CP) is abacterial, but is it true? The propose is – to estimate a spectrum of chronic abacterial prostatitis and estimate efficiency of complex treatment.Materials and Methods. Fifty six patients with chronic abacterial prostatitis 3-a category were enrolled in this study: first group (28 patients) received standard treatment and additionally - panavir, and second group (also 28 patients) - standard treatment only. All patients were examined by standard approach, including polimerase chain reaction on intracellular pathogens. Complex therapy was unique and included: doxiciclin, famcyclovir, pathogenetic therapy. Efficiency was estimated by NIH-CPSI scale and by eradication of pathogens.Results. All patients had chronic abacterial prostatitis 3-a category. Followed pathogens were revealed: Chlamydia trachomatis (17 patients), Ureaplasma urealyticum (15 patients), Mycoplasma genitalium (22 patients), virus Herpes (9 patients). These pathogens formally are not etiological factor, but in fact they maintain inflammation in the prostate. M. tuberculosis was not found. In first group total scores decreased from 20.9 to 7.9, in second group - from 20.8 to 16.3). In three months, pathogens were 17.8% patients больных in first group, and in 42.8% in second group; accordingly efficiency of standard treatment was 57,2%, and in combination with panavir – 82.2%.onclusion. Examination on intracellular pathogens as well as viruses is indicated for patients with chronic abacterial prostatitis 3-a category. Standard therapy in cobination with panavir significantly imorives results of the treatment. Low efficiency of standard therapy may be explained both by secondary immunodefficiency and by myofascial syndrome.