Breaking in and busting out: cell-penetrating peptides and the endosomal escape problem

Cell-penetrating peptides (CPPs) have long held great promise for the manipulation of living cells for therapeutic and research purposes. They allow a wide array of biomolecules from large, oligomeric proteins to nucleic acids and small molecules to rapidly and efficiently traverse cytoplasmic membr...

Full description

Bibliographic Details
Main Authors: LeCher Julia C., Nowak Scott J., McMurry Jonathan L.
Format: Article
Language:English
Published: De Gruyter 2017-09-01
Series:Biomolecular Concepts
Subjects:
tat
Online Access:https://doi.org/10.1515/bmc-2017-0023