Potential Barriers to Human Hepatocyte Transplantation in MUP–uPARag2γC Mice

Primary human fetal and adult hepatocytes have been considered feasible donor cell sources for cell transplantation. We compared the engraftment efficiencies between adult human, fetal human, and adult porcine hepatocytes after transplantation into MUP–uPA tg(+/+) Rag2 -/- γC -/- mice. Transplantati...

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Bibliographic Details
Main Authors: Junji Komori, Aaron D. Deward, Roberto Gramignoli, Stephen C. Strom, Paulo Fontes, Eric Lagasse PharmD, Ph.D.
Format: Article
Language:English
Published: SAGE Publishing 2014-12-01
Series:Cell Transplantation
Online Access:https://doi.org/10.3727/096368913X672046