Ctdp1 deficiency leads to early embryonic lethality in mice and defects in cell cycle progression in MEFs

RNA polymerase II subunit A Carboxy-Terminal Domain Phosphatase 1 (CTDP1), a member of the haloacid dehalogenase superfamily phosphatases, has a defined role in transcriptional regulation, but emerging evidence suggests an expanded functional repertoire in the cell cycle and DNA damage response. In...

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Bibliographic Details
Main Authors: Fangfang Qiao, Henry C.-H. Law, Kimiko L. Krieger, Emalie J. Clement, Yi Xiao, Shannon M. Buckley, Nicholas T. Woods
Format: Article
Language:English
Published: The Company of Biologists 2021-01-01
Series:Biology Open
Subjects:
Online Access:http://bio.biologists.org/content/10/1/bio057232