Polymer substrate with surface solvent reservoir for polymer-spray mass spectrometric analysis of hydrophilic drugs

Polymer substrate with surface solvent reservoir for polymer-spray mass spectrometric analysis of hydrophilic drugs

Nonporous, hydrophobic organosiloxane (OSX) polymers with surface reservoirs were developed as sampling supports in polymer-spray mass spectrometry (polyS-MS) for the detection and quantification of hydrophilic drugs, ethyl glucuronide (logP -1.8) and vancomycin (logP -4.4), and a slightly hydrophob...

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Bibliographic Details
Main Authors:	Maria T. Dulay, Cornelia L. Boeser, Katherine L. Walker, Clara Feider, Richard N. Zare
Format:	Article
Language:	English
Published:	Elsevier 2021-12-01
Series:	Talanta Open
Subjects:	Polymer spray mass spectrometry Surface solvent reservoir Hydrophilic drugs
Online Access:	http://www.sciencedirect.com/science/article/pii/S2666831921000187

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