Extra cellular matrix derived metabolite regulates angiogenesis by FasL mediated apoptosis.

OBJECT: Antiangiogenic treatments are beginning to give promising outcomes in many vascular diseases including tumor angiogenesis. In this current study the antiangiogenic and pro-apoptotic actions of α1(IV)NC1 and its N- and C- peptides α1S1(IV)NC1, α1S2(IV)NC1 were investigated in-vitro and in-viv...

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Bibliographic Details
Main Authors: Raj K Verma, Venugopal Gunda, Smita C Pawar, Yakkanti Akul Sudhakar
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3851695?pdf=render