Structural and functional studies of phosphoenolpyruvate carboxykinase from Mycobacterium tuberculosis.

Structural and functional studies of phosphoenolpyruvate carboxykinase from Mycobacterium tuberculosis.

Tuberculosis, the second leading infectious disease killer after HIV, remains a top public health priority. The causative agent of tuberculosis, Mycobacterium tuberculosis (Mtb), which can cause both acute and clinically latent infections, reprograms metabolism in response to the host niche. Phospho...

Full description

Bibliographic Details
Main Authors:	Iva Machová, Jan Snášel, Jiří Dostál, Jiří Brynda, Jindřich Fanfrlík, Mahavir Singh, Ján Tarábek, Ondřej Vaněk, Lucie Bednárová, Iva Pichová
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2015-01-01
Series:	PLoS ONE
Online Access:	http://europepmc.org/articles/PMC4370629?pdf=render

Similar Items

The Role of Cysteine Residues in Catalysis of Phosphoenolpyruvate Carboxykinase from Mycobacterium tuberculosis.
by: Iva Machová, et al.
Published: (2017-01-01)

The purification and characterization of phosphoenolpyruvate carboxykinase
by: Chang, Huei-Che
Published: (2017)

Structural and functional studies of phosphoenolpyruvate carboxykinase
by: Cotelesage, Julien Joseph Hubert
Published: (2007)

Phosphoenolpyruvate carboxykinase in Arabidopsis thaliana (L.)
by: Malone, Susan
Published: (2002)

Phosphofructokinases A and B from <i>Mycobacterium tuberculosis</i> Display Different Catalytic Properties and Allosteric Regulation
by: Jan Snášel, et al.
Published: (2021-02-01)

Regulation of phosphoenolpyruvate carboxykinase in leaves of Panicum maximum
by: Acheson, Richard Mervyn
Published: (1999)

The Novel Role of Mitochondrial Phosphoenolpyruvate Carboxykinase in Cancer
by: Pei-Huan Wu, et al.
Published: (2007)

Mechanism of Catalysis by Escherichia coli Phosphoenolpyruvate Carboxykinase
Published: (2015)

Cloning and expression of phosphoenolpyruvate carboxykinase from Escherichia coli
by: Xiaoliang HE, et al.
Published: (2019-04-01)

Biological Evaluation of a Mitochondrial Phosphoenolpyruvate Carboxykinase Inhibitor
by: Sergio Rodríguez-Arévalo, et al.
Published: (2019-09-01)

The role of phosphoenolpyruvate carboxykinase in the periparturient and ketotic dairy cow
by: Duncan, Jennifer S.
Published: (2012)

Function of phosphoenolpyruvate carboxykinase in mammary gland epithelial cells[S]
by: Chang-Wen Hsieh, et al.
Published: (2011-07-01)

Phosphoenolpyruvate carboxykinase and the critical role of cataplerosis in the control of hepatic metabolism
by: Kalhan Satish C, et al.
Published: (2005-11-01)

Crystallographic studies of <i>Escherichia coli</i> phosphoenolpyruvate carboxykinase
by: Matte, Alan Michael
Published: (1996)

Phosphoenolpyruvate carboxykinase in cell metabolism: Roles and mechanisms beyond gluconeogenesis
by: Shuo Yu, et al.
Published: (2021-11-01)

The Role of Tyrosine 207 in the Reaction Catalyzed by Saccharomyces cerevisiae phosphoenolpyruvate carboxykinase
by: Cherie Andrade, et al.
Published: (2010-01-01)

Effects of maternal dietary carbohydrate on phosphoenolpyruvate carboxykinase development in the fetus and neonate
by: Liu, Xu-Jing
Published: (1995)

Studies on phosphoenolpyruvate carboxykinase and citrate synthase in Escherichia coli, strain B
by: Wright, Jim Alexander
Published: (2013)

Studies on phosphoenolpyruvate carboxykinase and citrate synthase in Escherichia coli, strain B
by: Wright, Jim Alexander
Published: (2013)

Inhibition of Pig Phosphoenolpyruvate Carboxykinase Isoenzymes by 3-Mercaptopicolinic Acid and Novel Inhibitors.
by: Jorge Hidalgo, et al.
Published: (2016-01-01)

Phosphoenolpyruvate carboxykinase and ornithine decarboxylase genes : allelic variations and associations with traits in poultry
by: Parsanejad, Reza
Published: (2003)

Identification of phosphoenolpyruvate carboxykinase 1 as a potential therapeutic target for pancreatic cancer
by: Xiao-ren Zhu, et al.
Published: (2021-10-01)

The role of phosphoenolpyruvate carboxykinase in nitrogen remobilisation from senescing Arabidopsis and tobacco leaves
by: Leiss, Anna Elizabeth
Published: (2009)

Characterization of interaction and ubiquitination of phosphoenolpyruvate carboxykinase by E3 ligase UBR5
by: Qingya Shen, et al.
Published: (2018-12-01)

Inhibition of phosphoenolpyruvate carboxykinase blocks lactate utilization and impairs tumor growth in colorectal cancer
by: Emily D. Montal, et al.
Published: (2019-08-01)

Structural determinants for subnanomolar inhibition of the secreted aspartic protease Sapp1p from Candida parapsilosis
by: Jiří Dostál, et al.
Published: (2021-01-01)

Rapid nitration of adipocyte phosphoenolpyruvate carboxykinase by leptin reduces glyceroneogenesis and induces fatty acid release.
by: Anne-Marie Jaubert, et al.
Published: (2012-01-01)

Succinate Dehydrogenase-Regulated Phosphoenolpyruvate Carboxykinase Sustains Copulation Fitness in Aging C. elegans Males
by: Jimmy Goncalves, et al.
Published: (2020-04-01)

O-GlcNAcylation mediates the control of cytosolic phosphoenolpyruvate carboxykinase activity via Pgc1α.
by: Pedro Latorre, et al.
Published: (2017-01-01)

Mitochondrial phosphoenolpyruvate carboxykinase (PEPCK-M/PCK2), phosphoglycerate dehydrogenase (PHGDH) and muscle cell growth
by: Brearley, Madelaine C.
Published: (2018)

Correction: O-GlcNAcylation mediates the control of cytosolic phosphoenolpyruvate carboxykinase activity via Pgc1α.
by: PLOS ONE Staff
Published: (2017-01-01)

Phosphoenolpyruvate carboxykinase (Pck1) helps regulate the triglyceride/fatty acid cycle and development of insulin resistance in mice[S]
by: Carrie A. Millward, et al.
Published: (2010-06-01)

Structural and Thermodynamic Analysis of the Resistance Development to Pimodivir (VX-787), the Clinical Inhibitor of Cap Binding to PB2 Subunit of Influenza A Polymerase
by: Jiří Gregor, et al.
Published: (2021-02-01)

Nur77 suppresses hepatocellular carcinoma via switching glucose metabolism toward gluconeogenesis through attenuating phosphoenolpyruvate carboxykinase sumoylation
by: Xue-li Bian, et al.
Published: (2017-02-01)

Phosphoenolpyruvate carboxykinase 1 gene (Pck1) displays parallel evolution between Old World and New World fruit bats.
by: Lei Zhu, et al.
Published: (2015-01-01)

Inhibition by PGE₂ of glucagon-induced increase in phosphoenolpyruvate carboxykinase mRNA and acceleration of mRNA degradation in cultured rat hepatocytes
by: Püschel, Gerhard, et al.
Published: (1994)

RT-PCR Localization of Phosphoenolpyruvate Carboxykinase (PEPCK) mRNA in Rat Proximal Tubule Segments During Ammonium Chloride Acidosis
by: Craig, Matthew Rankin
Published: (1999)

The phosphoenolpyruvate carboxykinase (PEPCK) inhibitor, 3-mercaptopicolinic acid (3-MPA), induces myogenic differentiation in C2C12 cells
by: Madelaine C. Brearley, et al.
Published: (2020-12-01)

Phosphoenolpyruvate Carboxykinase, a Key Enzyme That Controls Blood Glucose, Is a Target of Retinoic Acid Receptor-Related Orphan Receptor α.
by: Hiroshi Matsuoka, et al.
Published: (2015-01-01)

Cloning of cDNAs for glyoxysomal malate dehydrogenase and for phosphoenolpyruvate carboxykinase of cucumber (Cucumis sativus L.) and gene expression in cotyledons during development
by: Kim, Dae-Jae
Published: (1994)