RBC-derived vesicles as a systemic delivery system of doxorubicin for lysosomal-mitochondrial axis-improved cancer therapy

RBC-derived vesicles as a systemic delivery system of doxorubicin for lysosomal-mitochondrial axis-improved cancer therapy

Introduction: Chemotherapeutic drugs are the main intervention for cancer management, but many drawbacks impede their clinical applications. Nanoparticles as drug delivery systems (DDSs) offer much promise to solve these limitations. Objectives: A novel nanocarrier composed of red blood cell (RBC)-d...

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Bibliographic Details
Main Authors: Shu-Hui Wu, Chia-Chu Hsieh, Szu-Chun Hsu, Ming Yao, Jong-Kai Hsiao, Shih-Wei Wang, Chih-Peng Lin, Dong-Ming Huang
Format: Article
Language:English
Published: Elsevier 2021-05-01
Series:Journal of Advanced Research
Subjects:
Drug delivery
Doxorubicin
Cancer chemotherapy
Nanoparticle
Lysosome
Mitochondria
Online Access:http://www.sciencedirect.com/science/article/pii/S2090123220302356

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http://www.sciencedirect.com/science/article/pii/S2090123220302356

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