Effect of N-Acetyl Cysteine administration to the degree of parasitemia and plasma interleukin-12 level of mice infected with plasmodium berghei and treated with artemisinin

Effect of N-Acetyl Cysteine administration to the degree of parasitemia and plasma interleukin-12 level of mice infected with plasmodium berghei and treated with artemisinin

Introduction Protection against malaria requires a cell-mediated immune response which is initiated by releasing interleukin-12 (IL-12) from antigen presenting cells (APC). N-Acetyl Cysteine (NAC) is a precursor of glutathione, while glutathione itself increases IL-12 production. Treatment with NAC...

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Bibliographic Details
Main Authors: Loeki E. Fitri, Hannatur Rosyidah, Nur P. Sari, Agustina T. Endarti
Format: Article
Language:English
Published: Faculty of Medicine Universitas Indonesia 2009-02-01
Series:Medical Journal of Indonesia
Online Access:http://mji.ui.ac.id/journal/index.php/mji/article/view/332

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