Replication and active demethylation represent partially overlapping mechanisms for erasure of H3K4me3 in budding yeast.

Histone modifications affect DNA-templated processes ranging from transcription to genomic replication. In this study, we examine the cell cycle dynamics of the trimethylated form of histone H3 lysine 4 (H3K4me3), a mark of active chromatin that is viewed as "long-lived" and that is involv...

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Bibliographic Details
Main Authors: Marta Radman-Livaja, Chih Long Liu, Nir Friedman, Stuart L Schreiber, Oliver J Rando
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-02-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC2816684?pdf=render