Chaperone-Mediated Stress Sensing in Mycobacterium tuberculosis Enables Fast Activation and Sustained Response

Gene regulatory networks controlling stress response in mycobacterial species have been linked to persistence switches that enable bacterial dormancy within a host. However, the mechanistic basis of switching and stress sensing is not fully understood.

Bibliographic Details
Main Authors: Satyajit D. Rao, Pratik Datta, Maria Laura Gennaro, Oleg A. Igoshin
Format: Article
Language:English
Published: American Society for Microbiology 2021-02-01
Series:mSystems
Online Access:https://journals.asm.org/doi/10.1128/mSystems.00979-20
Description
Summary:Gene regulatory networks controlling stress response in mycobacterial species have been linked to persistence switches that enable bacterial dormancy within a host. However, the mechanistic basis of switching and stress sensing is not fully understood.
ISSN:2379-5077