Natriuretic Peptides in Post-mortem Brain Tissue and Cerebrospinal Fluid of Non-demented Humans and Alzheimer’s Disease Patients

Natriuretic Peptides in Post-mortem Brain Tissue and Cerebrospinal Fluid of Non-demented Humans and Alzheimer’s Disease Patients

Animal studies suggest the involvement of natriuretic peptides (NP) in several brain functions that are known to be disturbed during Alzheimer’s disease (AD). However, it remains unclear whether such findings extend to humans. In this study, we aimed to: (1) map the gene expression and localization...

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Bibliographic Details
Main Authors: Simin Mahinrad, Marjolein Bulk, Isabelle van der Velpen, Ahmed Mahfouz, Willeke van Roon-Mom, Neal Fedarko, Sevil Yasar, Behnam Sabayan, Diana van Heemst, Louise van der Weerd
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-11-01
Series:Frontiers in Neuroscience
Subjects:
natriuretic peptides
brain
cerebrospinal fluid
Alzheimer disease
humans
gene expression
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2018.00864/full

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