Comparision of Immunohistochemical Expression of Cd10 in Odontogenic Cysts

• Main Authors: Deepa. K, M.S.Munisekhar, Charu Suri, Santosh Kumar Rajalbandi, Pradeep M.R., Pavan Gothe
• Format: Article
• Language: English
• Published: JCDR Research and Publications Private Limited 2014-11-01
• Series: Journal of Clinical and Diagnostic Research
• Subjects: cd10; dentigerous cyst; okc; radicular cyst
• Online Access: https://jcdr.net/articles/PDF/5126/9883_CE(NJ)_F(Sh)_PF1(NJ_Sh)_PFA(Sh)_PF2(PAG).pdf
• ISSN: 2249-782X; 0973-709X

Background: Expression of CD10 has been documented in various tumors like nasopharyngeal carcinoma, gastric carcinoma, squamous cell carcinoma, odontogenic tumors. Aim: To evaluate and compare CD10 expression in odontogenic cysts like radicular cyst, dentigerous cyst and odontogenic keratocyst (OKC). Materials and Methods: Total 60 cases were included in the study, comprising 20 cases each of radicular, dentigerous and odontogenic keratocyst. Each case was evaluated and compared for immunohistochemical expression of CD10. Results obtained were statistically analysed using ANOVA test followed by post hoc test Tukey-Kramer Multiple Comparisons Test for continuous variable and Chi-square test for discrete variable. Results: More number of cases showing sub-epithelial stromal CD10 expression were found in OKC among the cysts. Conclusion: CD10 expression was more in OKC compared to radicular and dentigerous cysts.