Doxorubicin-Loaded Melanin Particles for Enhanced Chemotherapy in Drug-Resistant Anaplastic Thyroid Cancer Cells

Doxorubicin-Loaded Melanin Particles for Enhanced Chemotherapy in Drug-Resistant Anaplastic Thyroid Cancer Cells

Anaplastic thyroid cancer (ATC) is highly aggressive and tends to develop drug resistance to standard chemotherapies. To overcome the drug resistance of ATC, we synthesized dopamine-melanin nanoparticles (MNPs) loaded with doxorubicin (Dox) molecules. The Dox-loaded MNPs (Dox-MNPs) developed exhibit...

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Bibliographic Details
Main Authors: Kun Wang, Shouju Wang, Kun Chen, Yijing Zhao, Xingqun Ma, Lin Wang
Format: Article
Language:English
Published: Hindawi Limited 2018-01-01
Series:Journal of Nanomaterials
Online Access:http://dx.doi.org/10.1155/2018/2603712

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