Reappraisal of Human HOG and MO3.13 Cell Lines as a Model to Study Oligodendrocyte Functioning

Reappraisal of Human HOG and MO3.13 Cell Lines as a Model to Study Oligodendrocyte Functioning

Myelination of neuronal axons is essential for proper brain functioning and requires mature myelinating oligodendrocytes (myOLs). The human OL cell lines HOG and MO3.13 have been widely used as in vitro models to study OL (dys) functioning. Here we applied a number of protocols aimed at differentiat...

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Bibliographic Details
Main Authors: Kim M. A. De Kleijn, Wieteke A. Zuure, Jolien Peijnenborg, Josje M. Heuvelmans, Gerard J. M. Martens
Format: Article
Language:English
Published: MDPI AG 2019-09-01
Series:Cells
Subjects:
cell line
differentiation
HOG
immature oligodendrocyte
Krabbe’s disease
oligodendrocyte
mature oligodendrocyte
MO3.13
myelin
multiple sclerosis
schizophrenia
SH-SY5Y
Online Access:https://www.mdpi.com/2073-4409/8/9/1096

Internet

https://www.mdpi.com/2073-4409/8/9/1096

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