TREATMENT WITH IMATINIB MESILAT IN CHRONIC MYELOGENOUS LEUKEMIA – OUR EXPERIENCE

<p>Background. Chronic myelogenous leukemia (CML) is a malignant clonal disorder of hematopoietic stem cell. In majority of patients we find reciprocal chromosomal translocation t (9.22) which result in fusion oncoprotein with tyrosine kinase activity. The normal ABL protein is involved in the...

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Bibliographic Details
Main Authors: Mateja Grat, Joško Vučkovič
Format: Article
Language:English
Published: Slovenian Medical Association 2004-12-01
Series:Zdravniški Vestnik
Subjects:
Online Access:http://vestnik.szd.si/index.php/ZdravVest/article/view/2419