Polymorphisms in the TOLLIP Gene Influence Susceptibility to Cutaneous Leishmaniasis Caused by Leishmania guyanensis in the Amazonas State of Brazil.

Polymorphisms in the TOLLIP Gene Influence Susceptibility to Cutaneous Leishmaniasis Caused by Leishmania guyanensis in the Amazonas State of Brazil.

INTRODUCTION:The clinical outcome to Leishmania-infection is determined by the individual adaptive immune T helper cell responses and their interactions with parasitized host cells. An early development of a proinflammatory immune response (Th1 response) is necessary for Leishmania-infection resolut...

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Main Authors: Felipe Jules de Araujo, Luan Diego Oliveira da Silva, Tirza Gabrielle Mesquita, Suzana Kanawati Pinheiro, Wonei de Seixas Vital, Anette Chrusciak-Talhari, Jorge Augusto de Oliveira Guerra, Sinésio Talhari, Rajendranath Ramasawmy
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC4479602?pdf=render

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http://europepmc.org/articles/PMC4479602?pdf=render

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