Galectin-9 suppresses B cell receptor signaling and is regulated by I-branching of N-glycans
Leukocytes are coated with glycans that modulate immune function through interactions with lectins. Here, the authors characterize the N-glycan repertoire of human tonsillar B cells. They report that Gal-9 is an intrinsic regulator of B cell activation that may differentially modulate BCR signaling...
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Bibliographic Details
| Main Authors: |
N. Giovannone,
J. Liang,
A. Antonopoulos,
J. Geddes Sweeney,
S. L. King,
S. M. Pochebit,
N. Bhattacharyya,
G. S. Lee,
A. Dell,
H. R. Widlund,
S. M. Haslam,
C. J. Dimitroff |
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| Format: | Article
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| Language: | English |
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| Published: |
Nature Publishing Group
2018-08-01
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| Series: | Nature Communications
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| Online Access: | https://doi.org/10.1038/s41467-018-05770-9
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