Celiac disease in pediatric patients according to HLA genetic risk classes: a retrospective observational study

Celiac disease in pediatric patients according to HLA genetic risk classes: a retrospective observational study

Abstract Background Celiac disease (CD) is an autoimmune enteropathy in which HLA-DQ haplotypes define susceptibility. Our aim was to evaluate if belonging to a certain HLA-DQ class risk could be associated to the clinical, serological and histological presentation of CD. Methods We performed a retr...

Full description

Bibliographic Details
Main Authors: Carlo Tolone, Marisa Piccirillo, Pasquale Dolce, Salvatore Alfiero, Mattia Arenella, Marina Sarnataro, Patrizia Iardino, Alessia Pucciarelli, Caterina Strisciuglio
Format: Article
Language:English
Published: BMC 2021-05-01
Series:Italian Journal of Pediatrics
Subjects:
Celiac disease
HLA-DQ2/ DQ8
Clinical and serological manifestation
Online Access:https://doi.org/10.1186/s13052-021-01052-1

Similar Items

Similar Items