Lack of Matrilin-2 favors liver tumor development via Erk1/2 and GSK-3β pathways in vivo.
Matrilin-2 (Matn2) is a multidomain adaptor protein which plays a role in the assembly of extracellular matrix (ECM). It is produced by oval cells during stem cell-driven liver regeneration. In our study, the impact of Matn2 on hepatocarcinogenesis was investigated in Matn2(-/-) mice comparing them...
Main Authors: | Alexandra Fullár, Kornélia Baghy, Ferenc Deák, Bálint Péterfia, Yvonne Zsák, Péter Tátrai, Zsuzsa Schaff, József Dudás, Ibolya Kiss, Ilona Kovalszky |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2014-01-01
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Series: | PLoS ONE |
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24691449/pdf/?tool=EBI |
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