Measuring the effects of particle orientation to improve the efficiency of electron cryomicroscopy

Measuring the effects of particle orientation to improve the efficiency of electron cryomicroscopy

A number of parameters influence the resolution of a cryo-EM structure. Here the authors investigate the effects of specimen orientation in single particle cryo-EM and present open-source software for rapidly assessing orientation distributions to improve data collection.

Bibliographic Details
Main Authors: Katerina Naydenova, Christopher J. Russo
Format: Article
Language:English
Published: Nature Publishing Group 2017-09-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-017-00782-3
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spelling doaj-e7fc8c59bb4b44a4bf246510f6cb7c7f2021-05-11T07:28:22ZengNature Publishing GroupNature Communications2041-17232017-09-01811510.1038/s41467-017-00782-3Measuring the effects of particle orientation to improve the efficiency of electron cryomicroscopyKaterina Naydenova0Christopher J. Russo1MRC Laboratory of Molecular BiologyMRC Laboratory of Molecular BiologyA number of parameters influence the resolution of a cryo-EM structure. Here the authors investigate the effects of specimen orientation in single particle cryo-EM and present open-source software for rapidly assessing orientation distributions to improve data collection.https://doi.org/10.1038/s41467-017-00782-3
collection DOAJ
language English
format Article
sources DOAJ
author Katerina Naydenova
Christopher J. Russo
spellingShingle Katerina Naydenova
Christopher J. Russo
Measuring the effects of particle orientation to improve the efficiency of electron cryomicroscopy
Nature Communications
author_facet Katerina Naydenova
Christopher J. Russo
author_sort Katerina Naydenova
title Measuring the effects of particle orientation to improve the efficiency of electron cryomicroscopy
title_short Measuring the effects of particle orientation to improve the efficiency of electron cryomicroscopy
title_full Measuring the effects of particle orientation to improve the efficiency of electron cryomicroscopy
title_fullStr Measuring the effects of particle orientation to improve the efficiency of electron cryomicroscopy
title_full_unstemmed Measuring the effects of particle orientation to improve the efficiency of electron cryomicroscopy
title_sort measuring the effects of particle orientation to improve the efficiency of electron cryomicroscopy
publisher Nature Publishing Group
series Nature Communications
issn 2041-1723
publishDate 2017-09-01
description A number of parameters influence the resolution of a cryo-EM structure. Here the authors investigate the effects of specimen orientation in single particle cryo-EM and present open-source software for rapidly assessing orientation distributions to improve data collection.
url https://doi.org/10.1038/s41467-017-00782-3
work_keys_str_mv AT katerinanaydenova measuringtheeffectsofparticleorientationtoimprovetheefficiencyofelectroncryomicroscopy
AT christopherjrusso measuringtheeffectsofparticleorientationtoimprovetheefficiencyofelectroncryomicroscopy
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