Characterization and Online Detection of Surfactin Isomers Based on HPLC-MSn Analyses and Their Inhibitory Effects on the Overproduction of Nitric Oxide and the Release of TNF-α and IL-6 in LPS-Induced Macrophages

A rapid method for characterization and online detection of surfactin isomers was developed based on HPLC-MSn (n = 1, 2, 3) analyses, and many surfactin isomers were detected and characterized from the bioactive fraction of the mangrove bacterium Bacillus sp. Inhibitory activities of surfactin isome...

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Bibliographic Details
Main Authors: Xin-Sheng Yao, Wen-Cai Ye, Yi Dai, Kui Hong, Jia Li, Zhi-Hong Yao, Hao Gao, Feng Zhao, Jin-Shan Tang
Format: Article
Language:English
Published: MDPI AG 2010-10-01
Series:Marine Drugs
Subjects:
Online Access:http://www.mdpi.com/1660-3397/8/10/2605/